| Category | Subcategory | End of Alzheimer’s Tests (2017) | Potential additions in 2021 |
| | Genetics | ApoE4 (gene most associated with amyloid) | Full genomics testing |
| | Cognitive Performance | Cognitive performance measured by CNSVital Signs, Brain HQ, MOCA (Montreal Cognitive Assessment) | |
| | Imaging | MRI that includes NeuroQuant Volumetrics to measure individual brain anatomy | Consider Qualitative EEG if patients want to get a functional baselineConsider PET scan to document amyloid |
| Type I | Inflammation | Hs-CRP (cardiac reactive protein), Albumin: Globulin ratio, Homocysteine, Glutathione | Organic Acids Testing if any metabolic issues |
| | Microbiome | Measure the gut and nasal microbiome | Genova Gi-Effects / Vibrant Gut ZoomerPeriopath for oral microbiome |
| Type 1.5 | Glucose metabolism | Insulin, Hemoglobin A1C, glucose, BMI (body mass index) | InBody Visceral Fat index |
| Type 2 | Fatty Acids | Omega 3:6 | Omega 9 / NutrEval if there are CIRS / toxins |
| | B Vitamins | Vitamins B1, B6, B12, Folate, Homocysteine | |
| | Other Vitamins | Vitamins C, 25OH D3, E | |
| | Hormones | Estradiol, progesterone, pregnenolone, testosterone, free testosterone, DHEA, Free T4, Free T3, TSH, rT3 | DUTCH testing if bioidentical hormones are an issue |
| Type 3 | Biotoxins / CIRS | C4a (complement 4a), TGFB1 (Trans Growth factor beta 1) , MSH (melanocyte stimulating hormone) HLA DRDQ (genetic test) Home based EMRI testing | MMP9 (matrix metalloproteinase 9), VEGF (vascular endothelial growth factor)Eliminate HLA-DRDQ if cost issueTest for specific biotoxins – Vibrant Tick Borne Disease panelHome based Actinomyces / Endotoxin testing by an Indoor Environmental Professional if mold is suspectedGENIE transcriptomics test if significant nuclear atrophy |
| | Metals, Minerals, Chemicals | Mercury, Lead, Arsenic, Cadmium, Copper, Zinc, Magnesium, Selenium, Potassium, Calcium | Quicksilver Whole Metals, follow-up TriTest if Mercury positiveChemical toxins by Great Plains Lab or Vibrant Iron studies – Fe, TIBC, Ferritin -if there are any signs of inflammation |
| Type IV | Lipids | Lipoproteins, LDL-Ox, Lipid Panel | |
| Type V | Cyrex panels | Cyrex 20, 2, 5 | |
Craig Tanio, MD 